VIRType SARS-CoV-2 (E484K)

The new SARS-CoV-2 variants often carrying multiple spike protein mutations as well as mutations in other genomic regions. The spike protein is key for viral entry and for vaccine development. Therefore, specific identification of theses variants is critical.

The VIRType SARS-CoV-2 (E484K) kit detects one single point mutation which result in the exchange of the amino acid Glutamic Acid to Lysine in the spike protein at position 484. 

The VIRType SARS-CoV-2 (E484K) kit provides all reagents for the rapid detection of several variant lineages on food and environmental surfaces as well as wastewater via RT-qPCR. The single point mutation referring to the E->K amino acid exchange is detected in the FAM^TM channel. As a reference, respective wild type RdRP-gene region is detected in the HEX^TM channel helping to confirm the presence of SARS-CoV-2.

The kit is validated for use with the Agilent AriaMx^TM, Bio-Rad CFX96 Touch^TM and the CFX96 Touch^TM Deep Well PCR platforms.

It is not intended for clinical diagnostics and should therefore be regarded as “For Research Use Only”.